C. elegans is an ideal model organism for exploring the mechanisms that determine lifespan. It is short-lived, its genome has been sequenced, and its utility for studying aging has been demonstrated by previous studies. Moreover, because similar molecular strategies are often used in C. elegans and mammals to achieve the same...
Senior and New Scholars Awards for Fred Hutchinson Cancer Research Center
Dr. Linda B. Buck
Fred Hutchinson Cancer Research Center
2000 senior Scholar Award in aging
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Dr. Antonio Bedalov
Fred Hutchinson Cancer Research Center
2002 new Scholar Award in aging
Chemical genetics relies on using small, cell-permeable molecules that interact with proteins and create a loss or a gain of function of proteins similarly to genetic mutations. The active compounds are obtained by the in vivo screening of libraries of chemicals for the desired cellular phenotype, similarly to finding mutants in traditional...
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Dr. Harlan Robins
Fred Hutchinson Cancer Research Center
2009 new Scholar Award in aging
The human immune system deteriorates with age in a process termed Immunosenescence, significantly impacting health and overall survival. The risk of death from infection increases dramatically by age 65, the efficacy of vaccination drops, and the increased rate of cancer seen in the elderly has been associated with loss of immune function.
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Dr. Daniel E. Gottschling
Fred Hutchinson Cancer Research Center
1998 senior Scholar Award in aging
The yeast Saccharomyces cerevisiae has become recognized as a model system for studying replicative senescence in eukaryotes. It permits easy genetic and physiological manipulations of cells, and a chance to examine aging cells in a homogeneous population. However, current methods of aging analysis in yeast are cumbersome and do not take... |
Dr. Jason Bielas
Fred Hutchinson Cancer Research Center
2009 new Scholar Award in aging
Some of the effects of aging are thought to originate from cell structures called mitochondria. Mitochondria are the cells' power sources; hundreds to thousands are present in every cell of the body, and each contains its own DNA that is separate from the cell nucleus, where the majority of our genes reside. The accumulation of mutations in...
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Funded Institutions
The Ellison Medical Foundation fosters research by means of grants-in-aid on behalf of investigators to universities and laboratories within the United States. Institutions receiving awards must be tax-exempt 501(c)(3) organizations or U.S. colleges or universities.
The Ellison Medical Foundation