It is generally agreed that sleep is essential in all complex organisms. "Essential" means that an animal fully deprived of sleep dies prematurely. Moreover, studies in people over almost fifty years indicate that both short sleep and long sleep correlate with reduced lifespan. This raises two possibilities: does covert morbidity...
Senior and New Scholars Awards for Brandeis University
Dr. Michael Rosbash
Brandeis University
2010 senior Scholar Award in aging
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Dr. John Lisman
Brandeis University
2009 senior Scholar Award in aging
It now seems likely that memory involves changes in the strength of synapses. These changes occur during learning and can lead to either an increase or decrease in the strength of synapses. Strong stimulation strengthens synapses, a process called long-term potentiation (LTP). Weaker stimulation leads to a weakening of synapses, a process... |
Dr. Gregory A. Petsko
Brandeis University
1998 senior Scholar Award in aging
Fragments of Alzheimer's polypeptide (APP) are found in senile plaques. Some fragments (Aβ 1-40 and 1-42) appear to be toxic to the brain. Dr. Petsko proposes to identify the enzyme(s) that produce these fragments and then, using Aβ-resistant mutants, determine how the Aβ peptides kill nerves. |
Dr. Michael Marr
Brandeis University
2009 new Scholar Award in aging
My lab is focused on investigating how an animal cell responds to developmental and environmental signals and how this response is manifested in changes in gene expression. The developmental, metabolic, and environmental signals a cell receives induce changes in both RNA and protein synthesis. Strict control of these processes is required for...
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Funded Institutions
The Ellison Medical Foundation fosters research by means of grants-in-aid on behalf of investigators to universities and laboratories within the United States. Institutions receiving awards must be tax-exempt 501(c)(3) organizations or U.S. colleges or universities.
The Ellison Medical Foundation